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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNB2
All Species:
15.76
Human Site:
S528
Identified Species:
34.67
UniProt:
Q92953
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92953
NP_004761.2
911
102563
S528
H
E
Q
L
N
N
T
S
S
S
S
P
Q
H
L
Chimpanzee
Pan troglodytes
XP_528164
911
102575
S528
H
E
Q
L
N
N
T
S
S
S
S
P
Q
H
L
Rhesus Macaque
Macaca mulatta
A4K2T1
529
58315
E158
C
C
R
A
R
Y
L
E
R
R
L
T
Q
P
R
Dog
Lupus familis
XP_543042
858
96045
L483
D
K
V
Q
D
N
H
L
S
P
N
K
W
K
W
Cat
Felis silvestris
Mouse
Mus musculus
A6H8H5
907
102331
S528
H
E
H
L
N
N
T
S
S
S
S
P
Q
H
L
Rat
Rattus norvegicus
Q63099
907
102077
S528
H
E
Q
L
N
N
T
S
S
S
S
P
Q
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507252
997
108259
L462
S
S
S
S
P
Q
H
L
N
V
Q
Q
L
E
D
Chicken
Gallus gallus
XP_425704
863
96938
K489
H
L
S
P
N
K
W
K
W
T
K
R
T
L
S
Frog
Xenopus laevis
NP_001079256
898
102391
S528
Q
E
Q
L
N
N
A
S
S
S
P
Q
H
L
S
Zebra Danio
Brachydanio rerio
XP_695259
820
92072
V451
A
K
R
N
G
S
I
V
S
M
N
L
K
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195169
1105
121957
R570
V
Q
W
R
A
N
D
R
A
H
S
G
M
Y
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
20.8
62.9
N.A.
92.7
92.8
N.A.
46.3
63.8
70.2
63.7
N.A.
N.A.
N.A.
N.A.
38.2
Protein Similarity:
100
99.8
32.7
72
N.A.
95.3
95.3
N.A.
56.7
72.7
78.6
73.1
N.A.
N.A.
N.A.
N.A.
53.7
P-Site Identity:
100
100
6.6
13.3
N.A.
93.3
100
N.A.
0
13.3
53.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
33.3
N.A.
93.3
100
N.A.
6.6
20
53.3
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
10
0
10
0
10
0
0
0
0
0
10
% A
% Cys:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
10
0
0
0
0
0
0
10
10
% D
% Glu:
0
46
0
0
0
0
0
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% G
% His:
46
0
10
0
0
0
19
0
0
10
0
0
10
37
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
19
0
0
0
10
0
10
0
0
10
10
10
10
0
% K
% Leu:
0
10
0
46
0
0
10
19
0
0
10
10
10
19
37
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
10
55
64
0
0
10
0
19
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
0
0
0
10
10
37
0
10
10
% P
% Gln:
10
10
37
10
0
10
0
0
0
0
10
19
46
0
0
% Q
% Arg:
0
0
19
10
10
0
0
10
10
10
0
10
0
0
10
% R
% Ser:
10
10
19
10
0
10
0
46
64
46
46
0
0
0
19
% S
% Thr:
0
0
0
0
0
0
37
0
0
10
0
10
10
0
0
% T
% Val:
10
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
10
0
10
0
0
0
10
0
10
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _